Human Genetic Determinants of Viral Diseases
نویسندگان
چکیده
منابع مشابه
Stem Cells Application in Modeling of Human Genetic Diseases
The use of animal models in modeling of human genetic disease has many advantages. In some cases, however, this method may not be applicable due to some limitations, such as differences in tissue composition, anatomy and physiology of humans and animals. Isogenic human disease models are a population of cells that are selected or engineered to model a specific genetic disease, in vitro. They ar...
متن کاملGenetic and Epigenetic Determinants in Autoinflammatory Diseases
The concept of autoinflammation has evolved over the past 20 years, beginning with the discovery that mutations in the Mediterranean Fever (MEFV) gene were causative of Familial Mediterranean Fever. Currently, autoinflammatory diseases comprise a wide range of disorders with the common features of recurrent fever attacks, prevalence of hyperreactive innate immune cells, and signs of inflammatio...
متن کاملViral diseases and human evolution.
The interaction of man with viral agents was possibly a key factor shaping human evolution, culture and civilization from its outset. Evidence of the effect of disease, since the early stages of human speciation, through pre-historical times to the present suggest that the types of viruses associated with man changed in time. As human populations progressed technologically, they grew in numbers...
متن کاملGenetic determinants of human hypertension.
Hypertension is a common trait of multifactorial determination imparting an increased risk of myocardial infarction, stroke, and end-stage renal disease. The primary determinants of hypertension, as well as the factors which determine specific morbid sequelae, remain unknown in the vast majority of subjects. Knowledge that a large fraction of the interindividual variation in this trait is genet...
متن کاملHuman Genetic Diseases
1Center for Experimental Medicine and Department of Neurology, TheThird Xiangya Hospital, Central South University, Changsha 410013, China 2Clinic and Policlinic for Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, 97080 Wurzburg, Germany 3Division of Neuromuscular Medicine, Davee Department of Neurology and Clinical Neurosciences, Northwestern University Feinberg School o...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annual Review of Genetics
سال: 2017
ISSN: 0066-4197,1545-2948
DOI: 10.1146/annurev-genet-120116-023425